AMMAN — The inside of your mouth is
the perfect place for bacteria to thrive: It is dark, it is warm, it is wet and
the foods and drinks you consume provide nutrients for them to eat.
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But when the harmful bacteria build up
around your teeth and gums, you are at risk of developing periodontal (or gum)
disease, experts say, which is an infection and inflammation in the gums and
bone that surround your teeth.
And such conditions in your mouth may
influence the rest of your body, said Kimberly Bray, a professor of dental
hygiene at the University of Missouri-Kansas City.
Exactly how oral bacteria affect your
overall health is still poorly understood, Bray said, since the existing
research is limited and no studies have established cause-and-effect. But some
conditions are more associated with oral health than others, experts say. Here
is what we know.
Issues linked with oral healthAbout 47 percent of people ages 30 and
older in the US have some form of periodontal disease, according to the Centers
for Disease Control and Prevention.
In its early stages, called gingivitis, the
gums may become swollen, red, or tender and may bleed easily. If left
untreated, gingivitis may escalate to periodontitis, a more serious form of the
disease where gums can recede, bone can be lost, and teeth may become loose or
even fall out.
There is a significant link between periodontitis and heart attack, stroke, plaque buildup in the arteries, and other cardiovascular conditions.
With periodontitis, bacteria and their
toxic byproducts can move from the surface of the gums and teeth and into the
bloodstream, where they can spread to different organs, said Ananda P.
Dasanayake, a professor of epidemiology at the New York University College of
Dentistry.
This can happen during a dental cleaning or
flossing, or if you have a cut or wound inside your mouth, he said.
If you have inflammation in the mouth that
is untreated, some of the proteins responsible for that inflammation can spread
throughout the body, Bray said, and potentially damage other organs.
DiabetesOf all the associations between oral health
and disease, the one with the most evidence is between periodontal disease and
diabetes, Bray said. And the two conditions seem to have a two-way
relationship, she added: Periodontal disease seems to increase the risk for
diabetes, and vice versa.
Researchers have yet to understand exactly
how this might work, but in one review published in 2017, researchers wrote
that the systemic inflammation caused by periodontal disease may worsen the
body’s ability to signal for and respond to insulin.
In another study, scientists found that diabetics
who were treated for periodontal disease saw their overall health care costs
decrease by 12 to 14 percent.
“You treat periodontal disease, you improve
the diabetes,” Dasanayake said.
PneumoniaIf large amounts of bacteria from the mouth
are inhaled and settle in the lungs, that can result in bacterial aspiration
pneumonia, said Dr Frank Scannapieco, a professor of oral biology at the
University at Buffalo School of Dental Medicine.
This phenomenon has been observed mainly in
patients who are hospitalized or older adults in nursing homes, and is a
concern for those who cannot floss or brush their teeth on their own, said Dr
Martinna Bertolini, an assistant professor of dental medicine at the University
of Pittsburgh School of Dental Medicine.
Preventive dental care such as with
professional teeth cleanings, or periodontal treatments like antibiotic
therapy, can lower the risk of developing this kind of pneumonia, Scannapieco
said.
Cardiovascular diseaseIn a report published in 2020, an international
team of experts concluded that there is a significant link between
periodontitis and heart attack, stroke, plaque buildup in the arteries, and
other cardiovascular conditions.
“Bacteria that are found in the mouth actually have been identified in the brain tissue of patients with Alzheimer’s.”
While researchers have not determined how
poor oral health might lead to worse heart health, some evidence suggests that
periodontal bacteria from the mouth may travel to the arteries in vascular
disease patients, potentially playing a role in the development of the disease.
And a 2012 statement from the American
Heart Association noted that inflammation in the gums has been associated with
higher levels of inflammatory proteins in the blood that have been linked with
poor heart health.
Some research also suggests that better
oral hygiene practices are linked with lower rates of heart disease.
Pregnancy complicationsA number of studies and reviews have found
associations between severe periodontal disease and preterm, low birth weight
babies, Dasanayake said, though more research is needed to confirm the link.
In a 2019 review, researchers found that
treating periodontal disease during pregnancy improved birth weight and reduced
the risk of preterm birth and the death of the fetus or newborn.
The best way to maintain good oral health is to follow the classic dental care advice, including brushing your teeth twice a day and flossing every day
And in a 2009 study, researchers found that
oral bacteria could travel to the placenta — potentially playing a role in
chorioamnionitis, a serious infection of the placenta and amniotic fluid that
could lead to an early delivery, or even cause life-threatening complications
if left untreated.
Research also suggests that bacteria from
your mouth may activate immune cells that circulate in the blood, causing
inflammation in the womb that could distress the placenta and fetal tissues.
There is long-standing research that periodontitis
may induce preterm birth in animals like mice, and that treating these
infections can protect against low birth weights and preterm birth.
DementiaResearchers have been increasingly
interested in the role of oral health in dementia, particularly Alzheimer’s
disease, Scannapieco said.
“Bacteria that are found in the mouth
actually have been identified in the brain tissue of patients with
Alzheimer’s,” he said, implying a potential role for them in the disease.
In a recent review, scientists noted that
oral bacteria — especially those related to periodontitis — could either affect
the brain directly via “infection of the central nervous system”, or indirectly
by inducing “chronic systemic inflammation” that reaches the brain.
However, there is no evidence that oral
bacteria alone could cause Alzheimer’s, the review authors wrote. Rather,
periodontal disease is just one “risk factor” among many for people who are
predisposed to Alzheimer’s or other forms of dementia.
Other conditionsOral bacteria have also been robustly
linked with a number of other conditions such as rheumatoid arthritis and
osteoporosis, Bray said. And emerging research is starting to link oral
bacteria with kidney and liver disease, as well as colorectal and breast cancers.
But more research is needed to confirm all
of these links, the experts said. And we still do not know if regular dental
care and periodontal treatments may help prevent or improve any of the
conditions mentioned above, Scannapieco said.
What you can doThe best way to maintain good oral health
is to follow the classic dental care advice, including brushing your teeth
twice a day and flossing every day, Scannapieco said.
“Not all people really appreciate their
oral health, and they’re only reminded of it when they have a toothache or some
pain,” he added. But it is important to be just as diligent and proactive about
your oral health as you are with exercise or diet or any other aspect of
well-being.
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