JOHANNESBURG, South Africa — South African scientists
have discovered a new COVID-19 variant, Omicron, with multiple mutations that
are thought to be highly contagious.
اضافة اعلان
The World Health Organization has designated it a variant of
concern and many countries are racing to try and contain it, banning flights
from southern Africa.
Scientists are working round-the-clock to dissect the
variant and try understand its behavior.
Here is a brief explainer of what is known so far about
Omicron — days after it emerged — as shared by South African scientists.
Origins
It is currently unclear where the variant originated from,
but South African scientists were the first to announce the discovery on November
25.
By that time cases had been detected in Hong Kong and
Botswana. A day later, Israel and Belgium also uncovered the variant.
Mutation
Scientists discovered the new variant with a "very
unusual constellation of mutations" on November 23.
Some of the mutations are already known, and affect
transmissibility and immune evasion, but many others are new.
It has the "most mutations we have seen to date",
said Professor Mosa Moshabela, Deputy Vice Chancellor of Research and
Innovation at the University of KwaZulu-Natal.
He said "some of these mutations we have seen before
like in Delta and Beta," but others they have not, and "we don't know
what the combination of those mutations will translate into."
Leading virologist Tulio de Oliveira said there were around
50 mutations overall, including 30 on the spike protein, the focus of most
vaccines as it is what enables the virus to enter cells.
Transmissibility
The pace at which the new daily COVID cases are increasing
in South Africa has left scientists suspecting it may be driven by the
transmissibility of the new variant.
Although not all are Omicron cases, the daily COVID
positivity rate rose this week from 3.6 percent on Wednesday, 6.5 percent on
Thursday, 9.1 percent on Friday and 9.2 percent on Saturday, according to
official data.
"Some of the mutations that are expressed have
previously been shown to enable the virus to spread easily and quickly, and
because of that we suspect that the (new variant) is going to spread
quickly," said Moshabela.
Immunity, severity
Some of the genetic mutations shown by the virus include
those known to enable the virus to evade immunity.
It is unclear though what the impact will be on vaccines.
As for the severity of the variant, scientists say it has
only come to light this week, giving little time for thorough analysis.
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